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What Is PRP / PRF Therapy?

When used cosmetically, PRP/PRF (platelet-rich plasma/platelet-rich fibrin) injections can treat hair loss, improve your skin’s texture, treat under-eye bags and dark circles, and reduce the appearance of scarring and stretch marks. It can also be combined with certain injectable fillers for the ultimate skin rejuvenation.

What Is Platelet-Rich Fibrin?

At VIVIFY, we primarily use platelet-rich fibrin – or “PRF” – as a non-surgical, long-term solution for several conditions. While it has been used in orthopedic injuries and procedures with excellent success, it can also be used in aesthetic medicine. By using the body’s natural healing powers of cytokines and growth factors, PRF therapy utilizes the patient’s own plasma that is injected or used topically to promote tissue repair and improve tissue quality. This can help reduce the signs of aging, such as fine lines and wrinkles, improve skin texture, and promote hair growth.

What Is the Difference Between PRP and PRF?

The main difference between PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) is how they are prepared. PRP therapy in Tampa is prepared by taking a small amount of the patient's blood and spinning it in a centrifuge to separate the platelets from the other blood components. This results in a concentrated solution of platelets that can be injected into the treatment area.

PRF, on the other hand, is prepared by spinning the blood at a slower speed, which allows for the formation of a fibrin matrix. This matrix contains a higher concentration of growth factors and cytokines, which can promote tissue regeneration and healing. PRF is considered more natural and biocompatible than PRP, as it does not require the addition of any anticoagulants or other chemicals.

PRF/PRP Therapy Before & After

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Benefits of PRF Therapy

  • Reduction in fine lines and wrinkles
  • Enhancement of skin texture and tone
  • Tightening of skin and improvement in skin laxity
  • Improvement of crepey skin
  • Generation of new collagen fibers

Am I a Good Candidate for PRF or PRP therapy?

PRF can provide many benefits for a patient, and most people are candidates for this treatment. Candidates for PRF injections include individuals looking for a non-surgical treatment option that uses their own blood to promote healing and regeneration. If you believe you are a good candidate for PRF therapy in Tampa, schedule a consultation with one of our qualified, board-certified providers to discuss what this treatment can do for you.

The PRF/PRP Procedure

This treatment generally takes an average of 30 minutes to 1 hour. We will draw your blood during this time and then separate the platelets. Depending on the indication, a local anesthetic may be used.

The number of injections will vary based on the condition we treat. Patients usually experience a significant improvement after the first or second administered injection.

Most patients report that PRF injections are not painful, but pain tolerance varies from patient to patient and will also depend on the area being treated. Pain can usually be easily managed with over-the-counter medications such as Tylenol.

PRF/PRP Options

  • Topical: on the skin for blemishes and scars, a process similar to microneedling
  • Subcutaneous injections: to restore volume and collagen to the face, this can also be combined with hyaluronic acid (HA) fillers for a “boosted” and volumized facial filler
  • As part of surgery (usually facial cosmetic surgery): PRF is applied to the undersurface of the skin and the edges of the wound, allowing patients to heal more quickly
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PRF/PRP Results

Your results will depend significantly on the area you targeted with the PRF treatment. There can also be variability from patient to patient. The exact number of injections will depend on the treatment plan you and your doctor will discuss before proceeding. Typically patients begin to see improvement after a single injection, but optimal results may require repeat treatments.

Why Choose VIVIFY PRF & PRP in Tampa?

At VIVIFY plastic surgery & medspa, we believe overall health and wellness are multidimensional, and aesthetics deserves to be regarded as highly as other facets. We recognize that everyone has a unique beauty, so we offer personalized treatment plans to address each patient's specific goals. Every treatment you receive is performed by an experienced, board-certified clinician with your safety at the forefront. We honestly care about your aesthetic outcomes, which is why we treat every patient like a member of our family, providing high-quality care in a safe environment.

PRF/PRP FAQ

How soon can I return to normal activities after PRF/PRP treatment?

Can PRF/PRP therapy be combined with other treatments?

Is there any downtime associated with PRF/PRP therapy?

How is the blood drawn and is it safe?

How many sessions will I need?

Is PRF/PRP therapy painful?

Can PRF/PRP therapy help with acne scars or sun damage?

Is PRF/PRP safe for all skin types and tones?

How soon can I return to normal activities after PRF/PRP treatment?

Most patients can return to their normal daily activities immediately following the procedure. Some mild redness, swelling, or tenderness at the injection site may occur, but these side effects typically resolve within 24–48 hours.

Can PRF/PRP therapy be combined with other treatments?

Yes! PRF and PRP are often used in conjunction with other aesthetic procedures to enhance results. Popular combinations include microneedling, dermal fillers, and laser treatments. Your provider will recommend the best pairings for your individual goals.

Is there any downtime associated with PRF/PRP therapy?

Downtime is minimal. Some patients experience mild bruising, swelling, or redness in the treated area, which generally resolves within a few days. Most clients resume work or social engagements the same or next day.

How is the blood drawn and is it safe?

A small sample of your blood is taken—similar to a routine blood test—using sterile, medical-grade equipment. Because PRF/PRP therapy uses your own biological material, there is virtually no risk of allergic reaction or rejection.

How many sessions will I need?

While many patients see noticeable improvement after just one session, a series of treatments may be recommended for best results—especially for concerns like hair restoration or deeper skin rejuvenation. Your provider will develop a tailored plan based on your needs.

Is PRF/PRP therapy painful?

The treatment is generally well tolerated. A topical numbing cream or local anesthetic may be used to ensure comfort. Most patients describe the sensation as mild pressure or a slight pinching feeling.

Can PRF/PRP therapy help with acne scars or sun damage?

Yes. PRF/PRP can be highly effective for improving the appearance of acne scars, sun damage, and uneven skin texture when injected or used topically after treatments like microneedling.

Is PRF/PRP safe for all skin types and tones?

Absolutely. Because PRF/PRP uses your own blood and doesn’t involve harsh chemicals or lasers, it is safe and effective for all skin types and tones.

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