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What Is PRP / PRF Therapy?

When used cosmetically, PRP/PRF (platelet-rich plasma/platelet-rich fibrin) injections can treat hair loss, improve your skin’s texture, treat under-eye bags and dark circles, and reduce the appearance of scarring and stretch marks. It can also be combined with certain injectable fillers for the ultimate skin rejuvenation.

What Is Platelet-Rich Fibrin?

At VIVIFY, we primarily use platelet-rich fibrin – or “PRF” – as a non-surgical, long-term solution for several conditions. While it has been used in orthopedic injuries and procedures with excellent success, it can also be used in aesthetic medicine. By using the body’s natural healing powers of cytokines and growth factors, PRF therapy utilizes the patient’s own plasma that is injected or used topically to promote tissue repair and improve tissue quality. This can help reduce the signs of aging, such as fine lines and wrinkles, improve skin texture, and promote hair growth.

What Is the Difference Between PRP and PRF?

The main difference between PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) is how they are prepared. PRP is prepared by taking a small amount of the patient's blood and spinning it in a centrifuge to separate the platelets from the other blood components. This results in a concentrated solution of platelets that can be injected into the treatment area.

PRF, on the other hand, is prepared by spinning the blood at a slower speed, which allows for the formation of a fibrin matrix. This matrix contains a higher concentration of growth factors and cytokines, which can promote tissue regeneration and healing. PRF is considered more natural and biocompatible than PRP, as it does not require the addition of any anticoagulants or other chemicals.

Benefits of PRF Therapy

  • Reduction in fine lines and wrinkles
  • Enhancement of skin texture and tone
  • Tightening of skin and improvement in skin laxity
  • Improvement of crepey skin
  • Generation of new collagen fibers

Am I a Good Candidate?

PRF can provide many benefits for a patient, and most people are candidates for this treatment. Candidates for PRF injections include individuals looking for a non-surgical treatment option that uses their own blood to promote healing and regeneration. If you believe you are a good candidate for PRF therapy in Tampa, schedule a consultation with one of our qualified, board-certified providers to discuss what this treatment can do for you.


This treatment generally takes an average of 30 minutes to 1 hour. We will draw your blood during this time and then separate the platelets. Depending on the indication, a local anesthetic may be used.

The number of injections will vary based on the condition we treat. Patients usually experience a significant improvement after the first or second administered injection.

Most patients report that PRF injections are not painful, but pain tolerance varies from patient to patient and will also depend on the area being treated. Pain can usually be easily managed with over-the-counter medications such as Tylenol.

Treatment Options

  • Topical: on the skin for blemishes and scars, a process similar to microneedling
  • Subcutaneous injections: to restore volume and collagen to the face, this can also be combined with hyaluronic acid (HA) fillers for a “boosted” and volumized facial filler
  • As part of surgery (usually facial cosmetic surgery): PRF is applied to the undersurface of the skin and the edges of the wound, allowing patients to heal more quickly
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Your results will depend significantly on the area you targeted with the PRF treatment. There can also be variability from patient to patient. The exact number of injections will depend on the treatment plan you and your doctor will discuss before proceeding. Typically patients begin to see improvement after a single injection, but optimal results may require repeat treatments.

Why Choose VIVIFY?

At VIVIFY plastic surgery & medspa, we believe overall health and wellness are multidimensional, and aesthetics deserves to be regarded as highly as other facets. We recognize that everyone has a unique beauty, so we offer personalized treatment plans to address each patient's specific goals. Every treatment you receive is performed by an experienced, board-certified clinician with your safety at the forefront. We honestly care about your aesthetic outcomes, which is why we treat every patient like a member of our family, providing high-quality care in a safe environment.

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